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Articles by Dr. Hoffman
55 articles on MCAS and POTS, mold illness, Lyme, hormones, mitochondria and the 7 Stages. All free to read.
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21+ Mast Cell Stabilizers for MCAS: Drug and Natural Options - 2
Best Antihistamine for MCAS: H1 and H2 Blocker Protocol - 3
Shoemaker Protocol: The 12 Steps for Mold Illness and CIRS - 4
MCAS vs Histamine Intolerance: What Is the Difference? - 5
MCAS Food Triggers: 10 Foods to Avoid and 10 Other Triggers - 6
Physical Symptoms of High Oxalates and Linked Conditions
Latest
Is Functional Medicine Dead? Why It Plateaued and What Comes Next
Food as Light Information: Why Seasonal, Local Eating Is Mitochondrial Medicine
The Fat Paradox: Omega-6 Deficiency, Not Seed Oils, Is the Problem
Living With MCAS: 12 Tips for Mast Cell Activation Syndrome
Lyme Disease Diagnosis: History, Symptoms and Lab Tests
ERMI Test and CIRS: How to Investigate Mold Exposure
All 55 articles
- Is Functional Medicine Dead? Why It Plateaued and What Comes NextFunctional medicine fixed what allopathic medicine missed, then stalled: it still treats the body as chemistry. Dr. Bruce Hoffman on why chronic illness outgrew it, and the seven-layer model that comes next.
- Food as Light Information: Why Seasonal, Local Eating Is Mitochondrial MedicineFood is not just fuel, it is structured sunlight your mitochondria are built to read. Dr. Bruce Hoffman on biophotons, mTOR and AMPK, and why diets that should work often don't until light, timing and season line up.
- The Fat Paradox: Omega-6 Deficiency, Not Seed Oils, Is the ProblemThe war on seed oils has it backwards. Most chronically ill patients are omega-6 deficient and over-supplemented with omega-3. Dr. Bruce Hoffman on membranes, the 4:1 ratio, and how to choose and test essential fats.
- Living With MCAS: 12 Tips for Mast Cell Activation SyndromeLiving with MCAS: 12 tips on how to manage mast cell activation syndrome, from foods to avoid to H1 and H2 blockers, herbs, sleep and stress.
- Lyme Disease Diagnosis: History, Symptoms and Lab TestsDr. Bruce Hoffman explains why Lyme disease diagnosis rests on clinical history and symptoms, not one positive lab test, and how co-infections differ.
- ERMI Test and CIRS: How to Investigate Mold ExposureThe ERMI test measures mold spores in home dust. Dr. Bruce Hoffman explains it alongside the CIRS symptoms questionnaire, VCS test and Shoemaker labs.
Biotoxin Illness Treatment: Pitfalls in Mold and CIRS CareBiotoxin illness treatment in mold and CIRS: why a urine mycotoxin test cannot diagnose it, when cholestyramine harms, and what to assess first.
AIP Sweet Potato Recipe: Apple Oatmeal BakeAIP oatmeal without oats: shredded garnet yams, sweet potato flour, ceylon cinnamon and apple sauce baked at 350F, served with homemade coconut milk.
Ancient Healing Techniques from Asclepius to DescartesAncient healing practices of the Asclepian temples, Hippocrates, Galen and Paracelsus, and why Dr. Hoffman says inner and outer healing must be balanced.- Best Antihistamine for MCAS: H1 and H2 Blocker ProtocolThe best antihistamine for MCAS: H1 and H2 blockers every 12 hours, Pepcid (famotidine) with levocetirizine, ketotifen at night and an 11-step plan.
Blood Sugar Stabilizing BiscuitsBlood sugar stabilizing biscuits made with almond flour, coconut flour, pastured eggs and cream, sweetened with stevia. Makes 6 large biscuits at 315F.
Cauliflower Buns Recipe: Low Carb and Gluten FreeCauliflower buns made with riced cauliflower, paleo flour, macadamia nut milk and pastured eggs: gluten free, low carb buns baked at 325F until golden.
Cell Membrane Supportive Shepherd’s PieA shepherd’s pie recipe with ground turkey thighs, leeks, root vegetables and peas under a white sweet potato mash made with ghee and fresh herbs.
What Is CIRS? Meaning, Symptoms, Criteria and TreatmentCIRS meaning explained: Shoemaker diagnostic criteria, the 37 symptoms, HLA gene testing, biomarkers like MSH, C4a and TGF beta-1, and treatment steps.
Hemopyrrollactamuria (HPU/KPU) and Chronic Lyme DiseaseHemopyrrollactamuria (HPU), or kryptopyrroluria (KPU), drains zinc, B6 and biotin. Its symptoms, testing and link to chronic Lyme disease.
MCAS Blood Tests and Urine Labs to Ask Your Doctor ForHow to test for MCAS: the blood and 24-hour urine tests Dr. Hoffman recommends, from plasma histamine and heparin to PGD2, and why samples must be chilled.
MCAS Consensus-2: Revised Diagnostic CriteriaDr. Bruce Hoffman on MCAS: the consensus-2 diagnostic criteria paper led by Dr. Lawrence Afrin, and how MCAS differs from systemic mastocytosis.
CIRS Shoemaker Protocol Evidence and Randomized TrialsIs there randomized trial evidence for the Shoemaker CIRS protocol and cholestyramine in mold illness? How evidence-based medicine and its flaws apply.
Frequently Asked Mold Questions: Cleaning After MoldAnswers to frequently asked mold questions: cleaning books, electronics, leather and dishes, HEPA vacuum filters, cars, friends' homes and ERMI testing.
Fresh and Feta-stic Avocado Summer SaladA fresh avocado summer salad with arugula, cherry tomatoes, snacking peppers, herbs and sheep feta, dressed with lemon, olive oil and sea salt.
What Is Functional Medicine? Principles and ApproachFunctional medicine is an integrative, science-based approach that weighs genetics, environment, nutrition and stress to treat causes of chronic disease.
Gas Stove Controversy: Indoor Air and Asthma RiskThe gas stove controversy: nitrogen dioxide, PM2.5 and benzene, what the asthma studies show, their limits, and how to reduce exposure.
Chocolate Chip and Coconut Cookies, Grain and Nut FreeGrain free, nut free chocolate chip and coconut cookies made with Ottos cassava flour, Tigernut flour and coconut sugar, plus a monk fruit sugar free swap.
Grain Free Sweet Potato RotiA grain free sweet potato roti made with cassava flour, ghee and sea salt, cooked in a cast iron skillet and suited to sweet or savoury fillings.
Chronic Illness Healing: Dr. Bruce Hoffman InterviewDr. Bruce Hoffman on chronic illness healing: early childhood trauma, family systems, health as a value, and his Seven Stages to Health and Transformation.- MCAS vs Histamine Intolerance: What Is the Difference?MCAS vs histamine intolerance: histamine intolerance is a subset of MCAS. Mast cells release histamine plus many other mediators. Here is the difference.
Does Prometrium Cause Weight Gain on HRT?Does Prometrium cause weight gain? Dr. Hoffman explains why synthetic Provera adds weight, and why rapid weight gain on HRT is usually fluid retention.
Common Household Toxins and How to Reduce ThemCommon household toxins like BPA, phthalates, PFOA and pesticides, where toxins in the home hide in air, water and food, and 13 steps to reduce them.
Chronic Illness and the Seven Layers of HealingDr. Bruce Hoffman tells Judy Cho why chronic illness needs healing at seven levels, from toxins, labs and the cell danger response to trauma and meaning.
Crohn's Disease, Vitamin D and Other IBD Risk FactorsHow vitamin D, mast cells (MCAS), smoking, NSAIDs and the gut microbiome shape the risk of Crohn's disease and ulcerative colitis: 26 risk factors.
Seven Stages to Health: Klinghardt's Five Levels ExpandedDr. Hoffman's ISEAI 2020 talk expands Klinghardt's five levels of healing into seven stages for complex illness, from environment to emotions and soul.
Andropause: Symptoms, Age, Testing and TreatmentAndropause, also called viropause or male menopause, usually begins at 40 to 45. Learn the symptoms, testosterone testing, treatment and other hormones.
Medications to Avoid With MCAS: Drugs and ExcipientsMCAS medications to avoid include beta blockers, opiates and some anesthetics, plus excipients like dyes, alcohol and povidone. How to spot a reaction.
Mast Cell Activation Syndrome (MCAS) and HistamineMCAS symptoms by organ system, from dry eyes, red face and bruising to tremors, plus histamine intolerance, glutathione, lab tests and treatment options.
MCAS Podcast: Mast Cell Activation Diagnosis and TreatmentIn this MCAS podcast, Dr. Bruce Hoffman explains how mast cell activation syndrome is diagnosed, which chilled lab tests help, and how it is treated.- 21+ Mast Cell Stabilizers for MCAS: Drug and Natural OptionsMast cell stabilizers for MCAS: drugs like cromolyn and ketotifen, plus natural mast cell stabilizers and supplements such as quercetin and DAO.
- MCAS Food Triggers: 10 Foods to Avoid and 10 Other TriggersA list of common MCAS food triggers, the 10 high histamine foods to avoid with MCAS, plus 10 non-food MCAS triggers and conditions linked to MCAS.
Mold Illness and CIRS: Symptoms, Misconceptions, TreatmentMold illness, or CIRS, causes symptoms from brain fog to fatigue. Learn 13 CIRS mold symptoms, 4 misconceptions and Dr. Hoffman's treatment steps.
Household Mold Remediation: Identifying and Removing MoldHousehold mold remediation step by step: ERMI and HERTSMI-2 testing, choosing a mold inspector, HEPA vacuuming, cleaning belongings and prevention.
NAD Supplement Benefits: What NAD+ Does and How to Raise ItNAD+ benefits explained: what an NAD supplement is, how NAD+ drives energy, DNA repair and sirtuins, and natural ways to raise NAD+ as you age.- Physical Symptoms of High Oxalates and Linked ConditionsPhysical symptoms of high oxalates include kidney stones, achy joints, cloudy urine and pelvic pain. How oxalate sensitivity arises and linked conditions.
MCAS Triggers, Testing and Treatment with Dr. Bruce HoffmanMCAS podcast with Dr. Bruce Hoffman: top triggers (early trauma, mold, food), why self-regulation comes first, testing and mast cell stabilizers.
Practicing the Medical Arts: A Seven-Level ApproachDr. Hoffman on Artist Decoded: practicing the medical arts across seven levels, from environment and biochemistry to values, family trauma and soul.
POTS Symptoms, Types and Diagnosis (Part I)What is POTS disease? POTS symptoms, heart rate criteria, the four types, links with MCAS and Ehlers-Danlos, likely causes and tilt-table testing.
Practical Tips on Exercise and Diet from Dr. Bruce HoffmanDr. Bruce Hoffman's exercise and diet tips: daily workouts, mineral salt and hydration, 1 to 1.25 g protein per pound lean weight, conscious eating.
Preventive and Treatment Strategies for COVID-19: Part 2COVID-19 prevention and treatment strategies from Dr. Hoffman: N95 masks, vitamins C and D, zinc, herbs, peptides and a cold and flu bath soak.
Anti-Inflammatory Coconut Curry Recipe with TurmericAn anti-inflammatory curry recipe with coconut milk, turmeric, ginger, cumin and coriander, chicken thighs or white fish, sweet potato and chicken broth.
Power Shake Ingredients: A Fatty Acid Recipe TemplatePower shake ingredients in Dr. Hoffman's fatty acid template: coconut milk, balanced oils and minerals, adjusted by testing, plus Bulletproof coffee.
Bredesen Protocol: 7 Things to Prevent Cognitive DeclineDr. Dale Bredesen's ReCODE approach to reversing Alzheimer's: six subtypes, the 36 holes in the roof, and 7 things to do now, from sleep to fasting.
Risks of HRT in Women: What the WHI Trials ShowRisks of HRT explained: what the WHI trials found on breast cancer, estrogen-alone therapy, and synthetic progestins vs bioidentical progesterone.- Shoemaker Protocol: The 12 Steps for Mold Illness and CIRSThe Shoemaker protocol for CIRS and mold illness in 12 steps: ERMI and HERTSMI-2 testing, cholestyramine dosing, MARCONS, lab corrections and VIP spray.
Mitochondria and Adrenal Fatigue: Dr. Bruce HoffmanDr. Bruce Hoffman explains why adrenal fatigue follows mitochondrial shutdown and the cell danger response, plus mast cells, histamine and fatty acids.
How Many People Have MCAS? Symptoms and MCAS TestsSome experts estimate 14 to 17 percent of the US population has MCAS. See common MCAS symptoms and the key MCAS tests, with their handling requirements.
Cell Danger Response Treatment: Phospholipids and ButyrateDr. Bruce Hoffman on cell danger response treatment: IGL mitochondrial testing, fatty acid panels, and supplements such as phospholipids and butyrate.
Medical Ketogenic Diet Food List for NeuroprotectionA medical ketogenic diet food list for neuroprotection: which vegetables, proteins and fats to eat or avoid, macros, fasting and keto basics for beginners.
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